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Focus County:
Kitui County
Baringo County
Bomet County
Bungoma County
Busia County
Elgeyo Marakwet County
Embu County
Garissa County
Homa Bay County
Isiolo County
Kajiado County
Kakamega County
Kericho County
Kiambu County
Kilifi County
Kirinyaga County
Kisii County
Kisumu County
Kitui County
Kwale County
Laikipia County
Lamu County
Machakos County
Makueni County
Mandera County
Meru County
Migori County
Marsabit County
Mombasa County
Muranga County
Nairobi County
Nakuru County
Nandi County
Narok County
Nyamira County
Nyandarua County
Nyeri County
Samburu County
Siaya County
Taita Taveta County
Tana River County
Tharaka Nithi County
Trans Nzoia County
Turkana County
Uasin Gishu County
Vihiga County
Wajir County
West Pokot County
National
Kwale, Kilifi, Tana River, Lamu, Taita-River Counties
Kwale, Siaya Counties
Kisumu, Machakos, Nyeri, Isiolo
Kisumu, Homabay, Siaya, Migori Counties
Kisumu, Kilifi, Uasin Gishu Counties
Kwale, Kilifi, Tana River, Lamu, Taita-Taveta, Mombasa Counties
Kisumu, Siaya Counties
Busia, Bungoma, Kakamega, Vihiga Counties
Mombasa, Taita Taveta Counties
Busia, Bungoma, Kakamega, Vihiga, Kericho, Homabay, Kisii, Nyamira, Migori, Siaya, Kisumu Counties
Bumgoma, Busia Counties
Kisumu, Kwale, Busia Counties
Kisumu, Busia Counties
Mombasa, Kilifi Counties
Kiambu, Muranga, Nyandarua Counties
Siaya, Bungoma Counties
Narok, Samburu Counties
Siaya, Nairobi Counties
Taita Taveta, Nairobi Counties
Kisumu, Kilifi, Kericho, Kisii, Baringo Counties
Kilifi, Nairobi Counties
Programme & Disease Area
Programme Area:
Non-Communicable Diseases
Biotechnology
Natural Products Research & Drug Development (NAPREDA)
Infectious and Parasitic Diseases
Public Health & Health Research Systems
Non-Communicable Diseases
Sexual, Reproductive, Adolescent & Child Health
Research Priority Area:
Vaccine Development
Diagnostics
Genetic Engineering
Bioinformatics
Biostatistics
dental population and health systems and policy
epidemiology
behavioural and social sciences
nutrition
environmental/ occupational health
oral health
Health care financing
governance and leadership and service delivery
Maternal health
child health
adolescent health
STIs
Gender Based Violence (GBV)
infertility
sexual dysfunction
family planning
harmful traditional practices
aging and sexual and reproductive health
gender and human rights
Virology
Bacteriology
Mycology
Helminthology
Neglected Tropical Diseases and Zoonotic diseases
Traditional medicine
conventional medicine and alternative medicine
Lifestyle diseases
obesity
diabetes
hypertension
drug and substance abuse
cardiovascular
cancer (Breast, cervix, prostrate, throat, stomach, ovaries and skin)
Road traffic accidents
domestic/occupational injuries
mental health
Disease Domain:
Research Methods:
Observation / Participant Observation
Surveys
Interviews
Focus Groups
Experiments
Secondary Data Analysis / Archival Study
Mixed Methods (combination of some of the above)
Research design broad classification:
Qualitative Research Design
Quantitative Research Design
Research Methods, additional classification:
Descriptive Research Design
Experimental Research Design
Correlational Research Design
Diagnostic Research Design
Explanatory Research Design
ICD11 Classification:
Narratives
Introduction:
Herbal usages for Urinary tract infections UTI in diabetes have been used for centuries in Kitui County. The plant Jatropha curcasis of numerous natural yields traditional healers in Kitui County have been using various portions of the plant in different ways including bacterial infections treatment. Non-Communicable Diseases in Kenya gives 28 deaths where 2 was diabetes. Prevalence of diabetes in Kitui County is at 29. High glucose level in urine provides a conducive environment for pathogenic microorganisms Escherichia coli whichis the utmost major cause of UTI at approximately 80 populating the colon
Objectives:
This experimental study was intended at assessing the antimicrobial efficacy of Jatropha curcasleaves and stem bark extracts singly on Escherichia colia knowngram-negative bacterium and a common contributing instrument of urinary tract infection UTI in diabetic females attending Kitui County hospital in Kitui County Kenya
Methodology:
This is an Experimental and Cross-sectional method of research in which the Escherichia coliclinicalisolates were obtained from diabetic females identified with UTI at Kitui County Referrals Hospital and transported to Mount Kenya University. CrudeJatropha Curcasleaves and stem barks were harvested from Kitui County and Phytochemistry analysis done atEast African Herbarium in the National Museums of Kenya then after were subjected to clinical isolates of Escherichia colifor antimicrobial efficacy by evaluating their Minimum Inhibition Concentration and Minimum Bactericidal Concentration at Mount Kenya University Microbiology Laboratory
Findings:
Results:
Minimum Inhibition Concentrations produced Negative results and thus Minimum Bactericidal Concentration procedure was not done. A prevalence rate of 69 of Escherichia coliisolates as the causative agent of UTIs in diabetic females of Kitui County Kenya was noted.
Conclusion:
This study showed thatJatropha curcasleaves and stem bark extracts singly and as a concoction are bacterial static against E. coliin Urinary Tract Infections of diabetic females and a prevalence rate of 69 of Escherichia coliclinical isolates as the causative agent of Urinary tract infection in diabetic females of Kitui County locality Kenya.
Recommendations:
1. Failure to proceed to Minimum BactericidalConcentration from Minimum Inhibition Concentration as it is shownin tables 4 and 5there wasa static indication of the plant extracts to E.coliorganism and thus further additional studies is worth onthe medicinal plant.2. There is need of further immunological analysis of Jatropha curcas crude extract of diabetic female with UTI for a bacterial static indicator may be a sign ofimmunological booster to the diabetic females with UTI.3. Follow up of this study using clinical isolates from different body parts is needed.4 Evaluation of adverse reactions is paramount
Key Words:
Jatropha curcas Escherichia coli Urinary tract infection UTIs
SMART Survey:
INDEX
INDICATOR
Results
WHZ -scores
Global Acute Malnutrition
Weight for height <-2 z and/or oedema
2.0% ( 1.0- 4.0)
Severe Acute Malnutrition
Weight for height <-3 z and/or oedema
0.0% ( 0.0- 0.0)
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Recent Contributors
JN Muttunga
KENYA MEDICAL RESEARCH INSTITUTE
D Mathu
CENTRE FOR PUBLIC HEALTH RESEARCH
Kariuki Ngumo
INSTITUTE OF TROPICAL AND INFECTIOUS DISEASES
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