Antimicrobial Susceptibility Patterns of Bacterial Isolates in Patients at Moi County Referral Hospital Voi
ntimicrobial resistance AMR is an increasing worldwide concern to global health. Infections caused by these resistant organisms increase morbidity mortality and treatment costs. This study was conducted at Moi County Referral Hospital Voi
The aim of this study was to identify bacterial isolates cultured from patient samples and their corresponding antimicrobial susceptibility patterns and to describe the WHO antibiotic resistant priority pathogens identified in the study population. Methodology This was a retrospective study carried out at Moi County Referral Hospital Voi.
This was a retrospective study carried out at Moi County Referral Hospital Voi. It involved a review of patient laboratory records for bacterial isolates cultured from pus and urine samples carried out in the years 2015-2018 and their antimicrobial susceptibility patterns. Information on the patients age and sex bacteria isolated antimicrobial susceptibility duration of admission and the patient outcome was extracted and entered into a data abstraction tool. Statistical analysis was done on IBM SPSS statistics software.
A total of 1098 cultures were carried out in pus and urine samples from the years 2015-2018 296 were positive. Isolates with complete records that were included in the study were 250 46 of them were excluded due to missing data. The samples were obtained from both inpatients and outpatients. Pus samples were 176/250 70.4 urine samples were 74/250 29.6. Samples from the outpatient department were 197/250 78.8 and 53/250 21.2 from the inpatient department. Gram negative bacteria were predominantly isolated 149/250 59.6 and gram positive bacteria were 101/250 40.4. The only gram positive isolate was S. aureus. Gram negative bacteria isolated included E. coli 28 Klebsiella spp 16 Pseudomonas spp 10 and Proteus spp 6. Resistance was observed with commonly used first-line antimicrobials such as penicillins macrolides sulfamethoxazole-trimethoprim and 3rd generation cephalosporins
theres a rising resistance to first-line antibiotics and noted emerging resistance to second line antimicrobials. This shows a need for antimicrobial surveillance and antibiotic stewardship in order to combat this rising surge in antimicrobial resistance
Publication Information
Focus County(s):
Taita Taveta County
Programme Area(s):
Non-Communicable Diseases
Research Priority Area(s):
Disease Domain(s):
Sickle cell disease
Document History:
Publication Date: 15.Jul.2019
Conference Title: